Reactions of Δ7-steroids. I. Formylation of Δ7 -cholesten-3-one

✍ Scribed by Peter Morand; S. Stavrić; D. Godin

• Book ID: 104250106
• Publisher: Elsevier Science
• Year: 1966
• Tongue: French
• Weight: 203 KB
• Volume: 7
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)99628-5

✦ Synopsis

In the last few years a nusher of naturally occurrlna C-4 monomethyl sterols (1) and triterpenes (2) have been isolated from plants and the fommr have also been extracted (3) Fran mamnallan tissue. The ideas regard@! the blopenetlc lnmllcatlans of these carpounds have been sunmarlzed by Richards and Rendrlckson ('0.

Rudles and Bloch (5) have reported the converslcn of A-hydroxymethylene-A7-cholesten-m to CO2 and cholesterol under aerobic condltlcns supportlnp: the view that the C-4 methyl group 1s oxidized nrlor to ellmlnation. Cn relnvestl~tlng the structure 01' this precursor Joe obtained evldence which indicated the presence of a C-2 substituted conrcpu7d.