𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Reactions of α′ dienolates with michael acceptors: a synthesis of bicyclo [2,2,2] octan-2-ones.

✍ Scribed by Ross A. Lee


Publisher
Elsevier Science
Year
1973
Tongue
French
Weight
176 KB
Volume
14
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Asymmetric sequential Michael reaction:
✍ Hiroto Nagaoka; Kaoru Kobayashi; Toshiaki Okamura; Yasuji Yamada 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 243 KB

The sequential Michael reaction of (S)-4,5-di-O-isopropylidenepent-2enoate la and lb with lithium enolate 2 afforded diastereo-and enantioselec--tively bicyclo[2.2.2]octane 2 and 6 (or 51, respectively. The adducts were efficiently converted into both enantiomeric keto aldehydes c-j-7 and (+)-I. Bic

Diastereoselective synthesis of bicyclo[
✍ Dietrich Spitzner; Peter Wagner; Arndt Simon; Karl Peters 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 203 KB

Several chiral acrylates (7b-f) react with kinetically controlled generated lithium dienolate 6a to form chiral bicyclot2.2.2loctanes 4 with modest d.e.. It was found, that the diastereoselection is improved, when the corrssponding trimethylsilyl ether 6b reacts with chiral acrylates under Lewis aci