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Reactions of (S)-(4-nitrophenyl)[(4S)-2-oxo-1,3-oxazolidin-4-yl]methyl methanesulfonate with alkali metal halides and lithium hydroxide. Synthesis of [(2R,3R)-3-(4-nitrophenyl)aziridin-2-yl]-methanol

โœ Scribed by Madesclaire, M.; Coudert, P.; Leal, F.; Tarrit, S.; Zaitseva, Yu. V.; Zaitsev, V. P.


Book ID
121483266
Publisher
Springer US
Year
2013
Tongue
English
Weight
314 KB
Volume
49
Category
Article
ISSN
0009-3122

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Diastereoselective Reaction of (1S,2S)-2
โœ M. Madesclaire; P. Coudert; V. Gaumet; V. P. Zaitsev; Yu. V. Zaitseva ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons โš– 24 KB ๐Ÿ‘ 1 views

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Resolution of 4-cyano-4-(4-nitrophenyl)h
โœ Osman Achmatowicz; Iwona Malinowska; Barbara Szechner; Jan K. Maurin ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 641 KB

Using (R)-or (S)-l-phenylethylamine as a resolving agent, (R)-and (S)-4-cyano-4-(4nitrophenyl)hexanoic acids have been isolated. Cyclization of each enantiomer, followed by reduction of the nitro group, afforded (R)-and (S)-aminoglutethimide of high (>99% ee) enantiomeric purity, respectively. The a