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Reactions of Nucleosides with 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU). Syntheses of N(3)-Methylene-Bridged Bis-uridines and Secouridine-Dinucleoside Analogs

✍ Scribed by Vesna Čaplar; Vinko Škarić


Book ID
102857318
Publisher
John Wiley and Sons
Year
1993
Tongue
German
Weight
689 KB
Volume
76
Category
Article
ISSN
0018-019X

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✦ Synopsis


IV. 93


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1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)
✍ Fan Zhang; Zhenjiang Liu; Jintao Liu 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 95 KB

## Abstract The reaction of chiral __N__‐(__tert__‐butanesulfinyl)ketimines and __α__,__β__‐unsaturated trifluoromethyl ketones catalyzed by DBU was achieved under mild conditions. 1,2‐Addition products, precursors of chiral trifluoromethylated 1,3‐amino alcohols, were obtained diastereoselectively