Reactions of nitroxides with sulfur-containing compounds, part IV: Synthesis of novel nitroxide (thio)ureas

✍ Scribed by Jerzy Zakrzewski; Maria Krawczyk

• Book ID: 102230006
• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 166 KB
• Volume: 17
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20228

✦ Synopsis

The reactions of 4-isothiocyanato-2,2, 6,6-tetramethylpiperidine-1-oxyl 2 and 4-isocyanato-2,2,6,6-tetramethylpiperidine-1-oxyl 3 with selected amines and lower alcohols give the corresponding novel thioureas 4, ureas 5, thiocarbamates 6, and carbamates 7, all bearing the nitroxyl moiety. The characteristic features of EI mass spectra of (thio)ureas 4 and 5 are described. Some of the synthesized thioureas 4, ureas 5, thiocarbamates 6, and carbamates 7 are moderately or weakly active against pathogenic fungi.