Reactions of nitroxides, part XI: O-Aryl phenylselenophosphonates bearing a nitroxyl moiety

✍ Scribed by Bogumiła Huras; Jerzy Zakrzewski; Maria Krawczyk

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 200 KB
• Volume: 22
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20667

✦ Synopsis

Abstract

O‐Aryl phenylselenophosphonates bearing a nitroxyl moiety were synthesized in the presence of pyridine in diethyl ether from 4‐hydroxy‐2,2,6,6‐tetramethylpiperidine‐1‐oxyl, and either phenyldichlorophosphine and elemental selenium in 9–35% yield or phenyldichlorophosphine selenide in 36–62% yield. O,O‐Diaryl phenylselenophosphonates and O,O‐bis(2,2,6,6‐tetramethyl‐1‐oxyl‐4‐piperidyl)phenylselenophosphonates were obtained as by‐products. O,O‐Diaryl phenylselenophosphonates were obtained from phenyldichlorophosphine selenide and 2 mol of phenols in 55–86% yield. Antifungal activity of some synthesized selenophosphonates was found. © 2011 Wiley Periodicals, Inc. Heteroatom Chem 22:137–147, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.20667