Reactions of Nitric Oxide with Vitamin B12 and Its Precursor, Cobinamide†
✍ Scribed by Sharma, Vijay S.; Pilz, Renate B.; Boss, Gerry R.; Magde, Douglas
- Book ID
- 111655490
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 200 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0006-2960
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## Abstract A new backbone‐modified vitamin B12 derivative with an unusual configuration at the cobalt center has been used for the identification of the two axial diastereomers of cyano–aqua cobinamides (Cbi) by using ^1^H NMR spectroscopy.
Rate constants for the reactions of 1 -and 2-hydroxyethyl radicals with O2 and NO were measured at room temperature by laser flash photolysis-photoionization mass spectrometry method. The results are as follows (in units of cm3 moleculec' s-I): CH>CHOH+O> ((2.8+0.2)x10-I'); CH,CHOH+NO ((2.4kO.6)XlWI