A new method converting thioamides to ketene S,S-acetals, which exhibits wide compatibility with olefin, ketone, ester and amide groups, has been described. Thioamides have proved to be synthetically very potential by the total synthesis of Vitamin Bl2 (construction of corrin molecule) by Woodward a
Reactions of ketene acetals—IX: The synthesis of naphthoquinones from benzoquinones
✍ Scribed by Jean-Louis Grandmaison; Paul Brassard
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- French
- Weight
- 864 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0040-4020
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AbstractÐThe [212]-cycloaddition reactions of ketene diethyl acetal with methyl acrylate and acrylonitrile were optimized. Highly ef®cient ketal cleavage to either 2-cyano-1-cyclobutanone or 2-methoxycarbonyl-1-cyclobutanone was achieved using formic acid. Among the numerous reduction methods attemp