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Reactions of anthranilamide with isocyanates: A new facile synthesis of 2,3-dihydro-5H-oxazolo[2,3-b]quinazolin-5-one and 3,4-dihydro-2H,6H-[1,3]oxazino[2,3-b]quinazolin-6-one [1]

✍ Scribed by Ji-Wang Chern; Fang-Jy Shish; Chau-Dung Chang; Chao-Han Chan; Kang-Chien Liu

Book ID: 112128992
Publisher: Journal of Heterocyclic Chemistry
Year: 1988
Tongue: English
Weight: 207 KB
Volume: 25
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570250411

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## Abstract The reaction of 3‐__N__‐(2‐mercapto‐4‐oxo‐4__H__‐quinazolin‐3‐yl)acetamide (**1**) with hydrazine hydrate yielded 3‐amino‐2‐methyl‐3__H__‐[1,2,4]triazolo[5,1‐__b__]quinazolin‐9‐one (**2**). The reaction of **2** with __o__‐chlorobenzaldehyde and 2‐hydroxy‐naphthaldehyde gave the corresp