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REACTIONS OF AMINES. VI. SYNTHESIS OF α-AMINO KETONES AND ACIDS FROM IMINO DERIVATIVES 1,2

✍ Scribed by Baumgarten, Henry E.; Dirks, Jerald E.; Petersen, James M.; Wolf, Donald C.


Book ID
118276854
Publisher
American Chemical Society
Year
1960
Tongue
English
Weight
284 KB
Volume
82
Category
Article
ISSN
0002-7863

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A Novel Amination Reaction with Diphenyl
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## Abstract The reaction of enolates of α‐unsubstituted carboxamides 3 with diphenyl phosphorazidate (DPPA) and di(__tert__‐butyl) dicarbonate (‘Boc anhydride’) in THF at −78° yielded 2‐{[(__tert__‐butoxy)carbonyl]amino}carboxamides 5 (__Scheme 2__) which are derivatives of α‐amino acids. In this r