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Reactions of 6-aminopyrimidines with 2-dimethylaminomethylenetetralone. Regiospecific Synthesis Of 5,6-Dihydrobenzo [h]pyrimido [4,5-b] quinolines

✍ Scribed by Jairo Quiroga; Braulio Insuasty; Henry Insuasty; Rodrigo Abonia; Antonio Ortíz; Adolfo Sánchez; Manuel Nogueras

Publisher: Journal of Heterocyclic Chemistry
Year: 2001
Tongue: English
Weight: 34 KB
Volume: 38
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570380203

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✦ Synopsis

Abstract

Benzo[h]pyrimido[4,5‐b]quinolines (3) have been synthesized via a regiospecific cyclocondensation reaction between 6‐aminopyrimidines (1) and 2‐dimethylaminomethylentetralone hydrochloride (2). The linear structure of the final compounds were determined by nmr measurements, especially by ^1^H,^1^H, ^1^H,^13^C COSY and DEPT experiments.

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