Reactions of {4-[Bis(2-chloroethyl)amino
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Diana Florea-Wang; Inna Ijäs; Kristo Hakala; Jorma Mattinen; Juhani Vilpo; Jari
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Article
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2007
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John Wiley and Sons
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English
⚖ 246 KB
## Abstract Phenylacetic acid mustard (PAM; **2**), a major metabolite of the anticancer agent chlorambucil (CLB; **1**), was allowed to react with 2′‐deoxyadenosine (dA), 2′‐deoxyguanosine (dG), 2′‐deoxycytidine (dC), 2′‐deoxy‐5‐methylcytidine (dMeC), and thymidine (T) at physiological pH (cacodyl