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Reactions of 3-([(trifluoromethyl)sulfonyl]oxy)-1H-indole derivatives with diamines and carbon nucleophiles. Synthesis of 6H-indolo[2,3-b]quinoxaline derivatives

✍ Scribed by Béatrice Malapel-Andrieu; Jean-Yves Mérour

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
812 KB
Volume
54
Category
Article
ISSN
0040-4020

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✦ Synopsis

Indolic triflate reacted with 1,2-diamines to afford pyrazino[2,3-b]indole or indolo[2,3-b] quinoxaline. Carbon nucleophiles such as malonate derivatives also reacted with indolic triflate in absence of palladium catalyst to afford 2-(3-oxo-2,3-dihydro-1H-2-indolyliden) malonate derivatives.

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Reactions of 1,2-Bis(1H-indol-2-yl)ethan
Reactions of 1,2-Bis(1H-indol-2-yl)ethane: Formation of Indolo[2,3-c]carbazole and Cyclohept[1,2-b:5,4-b′]bisindole Derivatives
✍ Jan Bergman; Tomasz Janosik; Larisa Yudina; Eric Desarbre; Göran Lidgren; Lennar 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 119 KB

1,2-Bis(1H-indol-2-yl)ethane (9) has been prepared and converted into indolo[2,3-c]carbazole (8) using palladium acetate in refluxing acetic acid. Reaction of 9 with CoF 3 in hot TFA led to isolation of cyclohept[1,2-b:5,4-b H ]bisindole derivatives 11 and 12, which could be elaborated into further