Reactions of 1,2,4,5-tetrazines with S-nucleophiles
✍ Scribed by S. G. Tolshchina; R. I. Ishmetova; N. K. Ignatenko; A. V. Korotina; I. N. Ganebnykh; V. A. Ol’shevskaya; V. N. Kalinin; G. L. Rusinov
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 407 KB
- Volume
- 60
- Category
- Article
- ISSN
- 1573-9171
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A one step synthesis of (di)alkylamino-substituted 1,2,4,5-tetrazines direct from 3,6-disubstituted-1,2-dihydro-1,2,4,5-tetrazine precursors is described. A comparative study revealed that the described method not only avoids the up-to-now required oxidation step but also lower reaction times and/or
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