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Reactions of 1,1-dicyano-2-bis-(trifluoromethyl)-ethylens with enamines

✍ Scribed by V.Yu. Tyutin; N.D. Chkanikov; A.F. Kolomietz; A.V. Fokin

Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 34 KB
Volume: 54
Category: Article
ISSN: 0022-1139
DOI: 10.1016/s0022-1139(00)83784-7

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✦ Synopsis

A novel reaction of 1,1-dicyano-2-bis (trifluoromethyl) ethylenes (I) with aryl amines in the presence of carbonyl compounds leading to the trifluoromethyl substituted derivatives of 1,4-dihydropyridine is found and investigated.

J X=CF,,CO,AIk

The cyclization reactions (I) with classic enamines are also studied.

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