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Reactions Catalyzed by Bacterial Cytochromes P450

โœ Scribed by Max J. Cryle; Jeanette E. Stok; James J. De Voss

Publisher
John Wiley and Sons
Year
2003
Weight
53 KB
Volume
34
Category
Article
ISSN
0931-7597

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## Abstract Testing the toxicities and biological activities of the human metabolites of drugs is important for development of safe and effective pharmaceuticals. Producing these metabolites using human cytochrome P450s is difficult, however, because the human enzymes are costly, poorly stable, and