Reaction thin-layer chromatography of thiobarbiturates and barbiturates after bromination at the starting point
✍ Scribed by Rokus A. De Zeeuw; Jaap Wijsbeek
- Publisher
- Elsevier Science
- Year
- 1970
- Tongue
- English
- Weight
- 253 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1873-3778
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✦ Synopsis
Bromination of the spots at the starting point has been applied in the identification of closely related thiobarbiturates and barbiturates. The method proved to be very suitable to attack unsaturated derivatives and other reactive components, which can thus be distinguished from close-lying saturated and less reactive compounds, Oxidation reactions are mainly involved, taking place very rapidly. The adsorbent was shown to play an important role because addition of bromine to the substances dissolved in an organic solvent did not yield the same products as after bromination on the plate. The method seems to be likewise applicable to other classes of compounds. 2