Reaction of Tetrahydropyranyl Ethers with Triethylsilyl Trifluoromethanesulfonate-2,4,6-Collidine Combination: Speculation on the Intermediate, Efficient Deprotection, and Application to Efficient Ring-Closing Metathesis as a Tether.

Reaction of Tetrahydropyranyl Ethers wit

Reaction of Tetrahydropyranyl Ethers with Triethylsilyl Trifluoromethanesulfonate–2,4,6-Collidine Combination: Speculation on the Intermediate, Efficient Deprotection, and Application to Efficient Ring-Closing Metathesis as a Tether

✍ Hiromichi Fujioka; Takashi Okitsu; Takuya Ohnaka; Yoshinari Sawama; Ozora Kubo; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB 👁 1 views

## Abstract The reaction of tetrahydropyranyl (THP) ethers with triethylsilyl trifluoromethanesulfonate (TESOTf)–2,4,6‐collidine proceeded __via__ collidinium salt intermediates to give the alcohol and 4‐triethylsiloxybutanal in good yields. The structure of the intermediate was confirmed by ^1^H N