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Reaction of pyridine 1-oxides with isocyanates: Structure of the intermediates. Rationalization of rearrangements of six-membered heteroaromatic N-oxide derivatives

✍ Scribed by Rudolph A. Abramovitch; Ichiro Shinkai; Richard Van Dahm


Book ID
112123684
Publisher
Journal of Heterocyclic Chemistry
Year
1976
Tongue
English
Weight
117 KB
Volume
13
Category
Article
ISSN
0022-152X

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Reaction of 2-alkyl pyridine N-oxide der
✍ Daniele Andreotti; Emanuele Miserazzi; Arnaldo Nalin; Alfonso Pozzan; Roberto Pr πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 French βš– 389 KB

Treatment of 2-alkyl pyridine N-oxides with acylating reagents represents an established procedure for the introduction of oxygen functionality into alkyl group at the ortho position of N heteroaromatic rings. We have reported the first example of asymmetric Boekelheide rearrangement applied to a se