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Reaction of magnesium alkylidene carbenoids with lithium acetylides and lithium thiolates: a novel synthesis of conjugated enynes and vinyl sulfides

✍ Scribed by Masanori Watanabe; Masatomo Nakamura; Tsuyoshi Satoh


Book ID
108282923
Publisher
Elsevier Science
Year
2005
Tongue
French
Weight
504 KB
Volume
61
Category
Article
ISSN
0040-4020

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Treatment of lithium ester enolates with magnesium alkylidene carbenoids, generated from 1-chlorovinyl p-tolyl sulfoxides with isopropylmagnesium chloride via the sulfoxide-magnesium exchange reaction, gave b,c-unsaturated esters in moderate to good yields. When this reaction was conducted with the