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Reaction of dimethyl acetylenedicarboxylate with 2-ethyl-3-phenyl-2H-5,6-dihydro-1,2-oxazine

✍ Scribed by Goldberg, I.; Saad, D.; Shalom, E.; Shatzmiller, S.


Book ID
127344032
Publisher
American Chemical Society
Year
1982
Tongue
English
Weight
945 KB
Volume
47
Category
Article
ISSN
0022-3263

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## Abstract Preparation of 2,3‐Dimethyl‐5,6‐dihydro‐4__H__‐1,2‐oxaziniumiodide was achieved by N‐alkylation of 3‐methyl‐5,6‐dihydro‐4__H__‐1,2‐oxazine. Reactions with C‐nucleophiles led to the corresponding N‐methyl‐perhydro‐1,2‐oxazine derivatives. Reaction with sodium hydride in triglyme led to 3