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Reaction of .beta.-oxo esters with 2-amino-1,3,4-thiadiazoles. A reinvestigation

✍ Scribed by Kornis, Gabriel; Marks, Pamela J.; Chidester, Constance G.


Book ID
118070302
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
573 KB
Volume
45
Category
Article
ISSN
0022-3263

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Reaction of 2-amino-5-R-phenyl-!,3,4-thiadizoles with unsaturated acids and acid chlorides in the presence of trimethylamine takes place exclusively at the amino group to form the 2-carboxyalkyl-and 2-acylamino-derivatives, respectively. 2-Amino-l,3,4-thiadiazoles, including their acyl derivatives,