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Reaction of alkylating mutagens and carcinogens with nucleic acids: N-3 of guanine as a site of alkylation by N-methyl-N-nitrosourea and dimethyl sulphate

โœ Scribed by P.D. Lawley; D.J. Orr; S.A. Shah


Book ID
113135332
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
232 KB
Volume
4
Category
Article
ISSN
0009-2797

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PPh3-Catalyzed Reactions of Alkyl Propio
โœ Huimin Liu; QiongMei Zhang; Limin Wang; Xiaofeng Tong ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 283 KB ๐Ÿ‘ 2 views

## Abstract A new PPh~3~โ€catalyzed synthesis of alkyl 2โ€[aryl(tosylimino)methyl]acrylates from propiolate and __N__โ€tosylimine has been developed. Deuteriumโ€labelling experiments show that the reaction mechanism involves several hydrogenโ€transfer processes, which are not the turnoverโ€limiting step