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Reaction of acetone oxime with dialkylmalonyl chlorides. Synthesis of 2-(2-propenyl)isoxazolidine-3,5-diones and 2,2-bis-(2-(4,4-dialkylisoxazolidine-3,5-dione))propanes

✍ Scribed by Robert A. Izydore; Ronda G. Davis; Nancy W. Clements


Book ID
112128737
Publisher
Journal of Heterocyclic Chemistry
Year
1987
Tongue
English
Weight
260 KB
Volume
24
Category
Article
ISSN
0022-152X

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✍ Schick, Hans ;Roatsch, Birgit ;Schwarz, Hartmut ;Hauser, André ;Schwarz, Sigfrid 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 453 KB 👁 1 views

## Abstract In contrast to earlier reported unsuccessful experiments the Michael addition of prop‐2‐enal to 2‐methylcyclopentane‐1,3‐dione (1) affords 3‐(1‐methyl‐2,5‐dioxocyclopentyl)propanal (3) in 90% yield, if the reaction is carried out in water without a basic catalyst. This aldehyde is conve