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Reaction of 4-methyl-3,4-epoxytetrahydropyran with α-amino acids

✍ Scribed by U. G. Ibatullin; S. A. Vasil'eva; Z. Kh. Karimova; I. Z. Latypova; M. G. Safarov


Publisher
Springer US
Year
1989
Tongue
English
Weight
326 KB
Volume
25
Category
Article
ISSN
0009-3122

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Azomethine ylides from the reaction of 4
✍ Metwally, Saoud A. M. ;Aly, Moustafa F. ;Abd-Alla, Mohamed A. ;Atta, Ferial M. ; 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 255 KB 👁 1 views

## Abstract 4‐(Dicyanomethylene)‐3‐methyl‐1‐phenyl‐2‐pyrazoline‐5‐one (1) readily reacts with α‐amino acids and their esters by Michael addition and subsequent elimination of HCN to the adducts 2a–k. One of these, 2i (obtained from methyl glycinate), adds stereoselectively to __N__‐phenylmaleimide