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Reaction of 2-picolyllithium and 6-methyl-2-picolyllithium with vinyl(tert-butyl)acetylene

✍ Scribed by L. N. Cherkasov


Book ID
112348985
Publisher
Springer US
Year
1982
Tongue
English
Weight
177 KB
Volume
18
Category
Article
ISSN
0009-3122

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trrf-Butyl and 2,6-di(tert-butyl)-4-methylphenyl (RHT) cyclopropanecarboxylates (4, 6, 24, 25) are lithiated with LiN(i-Pr), and t -BuLi, respectively. Reactions with alkyl halides, aldehydes, acyl chlorides, and heteroelectrophiles give a-substituted BHT esters which can be cleaved (t-BuOK/H,O/THF)