Reaction of 2-halo-5-nitropyridines with hydroxide ion in dimethyl sulfoxide
β Scribed by Reinheimer, J. D.; Mayle, L. L.; Dolnikowski, G. G.; Gerig, J. T.
- Book ID
- 120080813
- Publisher
- American Chemical Society
- Year
- 1980
- Tongue
- English
- Weight
- 471 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0022-3263
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## Abstract The kinetics of the reaction of substituted anilines with 2βchloroβ5βnitropyridine were studied in dimethyl sulfonide (DMSO) and dimethyl formamide (DMF) at different amine concentrations and temperatures in the range 45β60Β°C. In both solvents the reaction was not a baseβcatalyzed one.
Substitution reactions of some parasubstituted anilines with 2-chloro-5nitropyridine and 2-bromo-5-nitropyridine were carried out conductometrically in dimethylsulfoxide/acetonitrile mixtures. The correlation of second order rate constants with Hammett's substituent constants yields a fairly linear