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Reaction kinetics of N-methyl-N′-nitro-N-nitrosoguanidine and N-ethyl-N′-nitro-N-nitrosoguanidine: Siv Osterman-Golkar, Mutation Res., 24 (1974) 219–226


Book ID
116036843
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
53 KB
Volume
25
Category
Article
ISSN
0027-5107

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␤-Propiolactone (BPL) and N-methyl-NЈ-nitro-N-nitrosoguanidine (MNNG) are two direct alkylating agents that induce multiple genetic lesions and tumors in the rodent stomach. We measured the kinetics of the induction of DNA damage by using the single-cell gel electrophoresis assay (SCGE) and the indu