Reaction between α-lactams and grignard reagents

✍ Scribed by Erach R. Talaty; Aubry E. Dupuy Jr.; Carolyn K. Johnson; Thomas P. Pirotte; Worth A. Fletcher; Richard E. Thompson

• Book ID: 104222643
• Publisher: Elsevier Science
• Year: 1970
• Tongue: French
• Weight: 159 KB
• Volume: 11
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)89452-6

✦ Synopsis

The reaction between methylmagnesium iodide and 1,3-di-tert-butylaziridinone (Ia) was described by Sheehan and Nafissi 2 to afford a novel, insertion-type product (IIIa) in 80% yield.