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Re-Treatment of Relapsed Indolent B-Cell Lymphoma With Rituximab

✍ Scribed by Tadahiko Igarashi; Tomoko Ohtsu; Hirofumi Fujii; Yasutsuna Sasaki; Yasuo Morishima; Michinori Ogura; Yoshitoyo Kagami; Tomohiro Kinoshita; Masaharu Kasai; Yoshio Kiyama; Yukio Kobayashi; Kensei Tobinai; Members of the IDEC-C2B8 Study Group


Publisher
Carden Jennings Publishing
Year
2001
Tongue
English
Weight
117 KB
Volume
73
Category
Article
ISSN
0925-5710

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Treatment of B-cell non-Hodgkin's lympho
✍ Stefano Sacchi; Massimo Federico; Giuseppe Dastoli; Claudia Fiorani; Giovanni Vi πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 232 KB

Rituximab is a chimeric anti CD-20 monoclonal antibody containing human IgG1 kappa constant regions, with murine variable regions. The anti-lymphoma effects of Rituximab are probably due to complement and antibody-dependent cell-mediated cytotoxicity, and induction of apoptosis. Phase II trials have