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Re-revision of the Stereo Structure of Piperidine Lactone, an Intermediate in the Synthesis of Febrifugine.

✍ Scribed by Yasuo Takeuchi; Kumiko Azuma; Hitoshi Abe; Kenji Sasaki; Takashi Harayama


Publisher
John Wiley and Sons
Year
2003
Weight
160 KB
Volume
34
Category
Article
ISSN
0931-7597

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Directed evolution of an esterase for th
✍ Uwe T. Bornscheuer; Josef Altenbuchner; Hartmut H. Meyer πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 123 KB πŸ‘ 2 views

The directed evolution of an esterase from Pseudomonas fluorescens using the mutator strain Epicurian coli XL1-Red was investigated. Mutants were as- sayed for their ability to hydrolyze a sterically hindered 3-hydroxy ester, which can serve as a building block in the synthesis of epothilones. Scree