Studies on osteosarcoma cell lines point to the potential importance of transforming growth factor beta (TGF beta) as an autocrine factor which controls the growth of human osteosarcomas. To define further the role of TGF beta isoforms in these neoplasms, a series of 27 osteosarcomas was studied usi
Re. Expression of transforming growth factor ? isoforms in osteosarcoma variants
β Scribed by Kloen, Peter
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 170 KB
- Volume
- 187
- Category
- Article
- ISSN
- 0022-3417
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Using immunohistochemistry, the expression, prevalence, and distribu-
## BACKGROUND. Transforming growth factor-β£ (TGF-β£) is a potent stimulator of cell proliferation in the liver and in liver tumors; however, its significance and association with hepatocyte proliferation remains unclear. ## METHODS. Expression of TGF-β£ and proliferation markers, such as prolifer
## Abstract Overexpression of the epidermal growth factor (EGF) receptor occurs frequently in ovarian cancer and is associated with poor patient prognosis. A constitutively active mutant EGF receptor termed variant III (EGFRvIII) has been detected at a high frequency in many human tumors, including
The mRNA expression and autoregulation of expression of the three isoforms of transforming growth factor-Ξ² (TGFΞ²) were examined in the mouse skin carcinogenesis model by northern analyses. We found that TGFΞ²3 mRNA levels followed a pattern similar to those of TGFΞ²1 during carcinogenesis: the levels