Re-evaluation of the dysfunction of mitochondrial respiratory chain in skeletal muscle of patients with Parkinson’s disease
✍ Scribed by K. Winkler-Stuck; E. Kirches; C. Mawrin; K. Dietzmann; H. Lins; C.-W. Wallesch; W. S. Kunz; F. R. Wiedemann
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 473 KB
- Volume
- 112
- Category
- Article
- ISSN
- 1435-1463
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Respiratory chain enzymes were studied in isolated mitochondria of two patients with mitochondrial myopathy. Both patients had been suffering from chronic progressive external ophthalmoplegia and abnormal muscular fatigability since late childhood. One of the patients exhibited the complete triad of
The quantification of mitochondrial enzyme activities in skeletal muscle samples of patients suspected of having mitochondrial myopathies is problematic. Therefore, we have evaluated different methods for the determination of activities cytochrome c oxidase and NADH:CoQ oxidoreductase in human skele