𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Re-evaluation of a transforming strain of epstein-barr virus from the burkitt lymphoma cell line, Jijoye

✍ Scribed by Takeshi Sairenji; Dr. Yorio Hinuma

Publisher
John Wiley and Sons
Year
1980
Tongue
French
Weight
584 KB
Volume
26
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The biological properties of Epstein‐Barr virus (EBV) from a Burkitt lymphoma cell line, Jijoye, were examined. The synthesis of virus capsid antigen (VGA) and early antigen (EA) in Jijoye cells was markedly enhanced by shift‐down of the temperature of incubation from 37°C to 33°C. Cultures of Jijoye cells at 33°C released a large amount of transforming EBV (10^5.2^ of 50% transforming doses/ml) into the culture fluid. However, no infectious virus was produced in all cultures at 37°C during the course of this study. The EBV (Jijoye EBV) from Jijoye line was found to possess only transforming activity, but not EA‐inducing activity. Jijoye EBV lacks adsorbing capacity to Jijoye cells, in contrast to P3HR‐l EBV which can adsorb to Jijoye cells. The Jijoye cells were highly susceptible to superinfection with P3HR‐l EBV as demonstrated by the induction of EA, VGA and infectious EBV. The EBV induced by the P3HR‐I EBV superinfection of Jijoye cells has also transforming activity but neither EA‐inducing activity nor adsorbing capacity to Jijoye cells.

📜 SIMILAR VOLUMES

Characteristics of cell lines derived fr
Characteristics of cell lines derived from human leukocytes transformed by different strains of epstein-barr virus
✍ Takato Katsuki; Yorio Hinuma 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 593 KB

## Abstract Variation of Epstein‐Barr virus (EBV) in respect to its effect on the properties of transformed cells was probed. Human umbilical cord leukocytes from six different individuals were transformed in vitro by either B95‐8 (B) or QIMR‐WIL (Q) strains of EBV and subsequently 12 lymphoblastoi

Different localization of epstein-barr v
Different localization of epstein-barr virus genome in two subclones of the burkitt lymphoma cell line namalwa
✍ Silvia Gargano; Daniela Caporossi; Giampiero Gualandi; Enrico Calef 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 524 KB

The Epstein-Barr virus genome contained in the Burkitt lymphoma line Namalwa was previously localized to the short arm of chromosome I. Analysis of a different subline of the same Namalwa line by means of Southern analysis carried out on genomic D N A , as well as in situ hybridization, showed a loc

Characterization of lymphoid cell lines
Characterization of lymphoid cell lines established from multiple epstein-barr virus (EBV)-induced lymphomas in a cotton-topped marmoset
✍ Harvey Rabin; Russell H. Neubauer; Ralph F. Hopkins III; Barnet M. Levy 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 French ⚖ 675 KB

## Abstract Inoculation of a cotton‐topped marmoset with cell‐free EBV, strain B95‐8, resulted in the induction of lymphomas in liver, spleen, and mesenteric lymph nodes. Continous suspension cell lines were established from tumor tissue from each of these three sites. Cells of each line were posit

Heterogeneity of epstein-barr virus. IV.
Heterogeneity of epstein-barr virus. IV. Induction of a specific antigen by EBV from two transformed marmoset cell lines in ramos cells
✍ K.-O. Fresen; M.-S. Cho; H. Zur Hausen 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 581 KB

## Abstract Infection of cells of the EBV‐genome‐negative human B‐lymphoma Ramos line with viral isolates obtained from two EBV‐transformed marmoset cell lines (B95/8; Nyevu) resulted in the induction of a nuclear antigen (RAM‐ag) apparently different from other EBV‐associated antigen complexes. Th