Re: Estimating the Benefits of PSA Screening
✍ Scribed by Monique J. Roobol; Fritz H. Schröder
- Book ID
- 113611662
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 107 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0302-2838
No coin nor oath required. For personal study only.
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When evaluating the bene"t of detecting cancer by screening we try to answer the question, &what would a screen detected subject's outcome have been if his/her cancer had progressed to clinical detection'. By &outcome' we mean survival time, cancer size and stage, lead time e!ects and more. Because
Variance estimators are derived for estimators of the average lead time and average benefit time due to screening in a randomized screening trial via influence functions. The influence functions demonstrate that these estimators are asymptotically equivalent to the mean difference, between the study