𝔖 Bobbio Scriptorium
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Re-engineering the target specificity of the insulin receptor by modification of a PTB domain binding site

✍ Scribed by van der Geer, Peter; Wiley, Sandra; Pawson, Tony


Book ID
110062288
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
190 KB
Volume
18
Category
Article
ISSN
0950-9232

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## Abstract The present paper reports the preparation and characterization of two neutralizing monoclonal antibodies (Mabs), called MST1 and MST2, which bind at the central loop of a long‐chain neurotoxin from cobra venom. The central loop is a critical region for the binding of the toxin to the ni