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Re: Cox-2 Inhibition Enhances the Activity of Sunitinib in Human Renal Cell Carcinoma Xenografts

✍ Scribed by Atala, Anthony

Book ID: 123008912
Publisher: Lippincott Williams and Wilkins
Year: 2013
Tongue: English
Weight: 75 KB
Volume: 190
Category: Article
ISSN: 0022-5347
DOI: 10.1016/j.juro.2013.05.071

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## Abstract The transcription factor nuclear factor‐κB (NF‐κB) has been shown to be constitutively activated in various human malignancies, including leukemia, lymphoma and a number of solid tumors. NF‐κB regulates the transcriptional of genes important for tumor invasion, metastasis and chemoresis