RCM in indoles. A new entry to the mitosene skeleton

✍ Scribed by Patxi González-Pérez; Leticia Pérez-Serrano; Luis Casarrubios; Gema Domı́nguez; Javier Pérez-Castells

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 83 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)00909-7

✦ Synopsis

The RCM metathesis reaction catalyzed by Grubbs' ruthenium catalyst is used with a series of 1,2-disubstituted indoles leading with excellent yields to tricyclic compounds. When applied to 1-allyl-2-vinylindoles this methodology allows a new entry to the mitosene skeleton.