Rationale for treating primary Sjögren’s syndrome patients with an anti-CD6 monoclonal antibody (Itolizumab)
✍ Scribed by Christelle Le Dantec, Ruby Alonso, Tinhinane Fali, Enrique Montero…
- Book ID
- 120898786
- Publisher
- Springer-Verlag
- Year
- 2013
- Tongue
- English
- Weight
- 474 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0257-277X
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📜 SIMILAR VOLUMES
## Abstract ## Objective To determine whether eyedrop administration of an anti‐CD4 monoclonal antibody (mAb) is effective in the treatment of Sjögren's syndrome (SS) using a mouse model of the disease. ## Methods The anti‐CD4 mAb was administered daily into the eyes of mice with SS from ages 4
## Abstract ## Objective To determine whether cytokine gene polymorphisms of interferon‐γ (IFNγ), interleukin‐6 (IL‐6), IL‐10, tumor necrosis factor α (TNFα), and transforming growth factor β1 (TGFβ1) predispose subjects to the development of primary Sjögren's syndrome (SS). ## Methods Single‐ba