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Rationale for the use of clodronate in osteoporosis

โœ Scribed by J. A. Kanis; E. V. McCloskey; P. Sirtori; S. Khan; D. Fern; K. Eyres; J. Aaron; M. N. C. Beneton


Publisher
Springer-Verlag
Year
1993
Tongue
English
Weight
820 KB
Volume
3
Category
Article
ISSN
0937-941X

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## Abstract In 1981, Chugai Pharmaceutical succeeded in marketing alfacalcidol, a prodrug of calcitriol, as a therapeutic agent for renal osteodystrophy. In 1983, Chugai succeeded in extending the application of alfacalcidol to the treatment of osteoporosis as well. Clinicians in Japan have accepte