Rational Design, Synthesis, Biological Evaluation, Homology and Docking Studies of Coumarin Derivatives as α1-Adrenoceptor Antagonists

ChemInform Abstract: α1-Adrenoceptor Ant

ChemInform Abstract: α1-Adrenoceptor Antagonists. Rational Design, Synthesis and Biological Evaluation of New Trazodone-Like Compounds.

✍ Laura Betti; Maurizio Botta; Federico Corelli; Monia Floridi; Paola Fossa; Gino 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

ChemInform Abstract: Design, Synthesis a

ChemInform Abstract: Design, Synthesis and Biological Evaluation of New Arylpiperazine Derivatives Bearing a Flavone Moiety as α1-Adrenoceptor Antagonists.

✍ Jing Jin; Xiao-Bing Wang; Ling-Yi Kong 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 35 KB

ChemInform Abstract: Computer-Based Drug

ChemInform Abstract: Computer-Based Drug Design, Synthesis and Biological Evaluation of New Pyrimidinone Derivatives Linked to Arylpiperazine and 2′-Carbethoxy-biphenylmethyl Moieties as α1-Adrenoceptor Antagonists and Angiotensin II AT1 Receptor Antagonists.

✍ M. A. H. Ismail; D. A. Abou El Ella; K. A. M. Abouzid; G. H. A. Al-Ansary 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 25 KB 👁 1 views

Design, Synthesis, and Biological Evalua

Design, Synthesis, and Biological Evaluation of α4β1 Integrin Antagonists Based on β-D-Mannose as Rigid Scaffold

✍ Jürgen Boer; Dirk Gottschling; Anja Schuster; Bernhard Holzmann; Horst Kessler 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 1 views

The tuning of protein ± protein interactions by small nonpeptidic molecules remains one of the great challenges in medicinal chemistry. Although already proposed in 1980 by Farmer, [1] only a few successful examples on the synthesis of peptidomimetics based on rigid scaffolds such as cyclohexane and

Design, Synthesis, and Biological Evalua

Design, Synthesis, and Biological Evaluation of α4β1 Integrin Antagonists Based on β-D-Mannose as Rigid Scaffold

✍ Jürgen Boer; Dirk Gottschling; Anja Schuster; Bernhard Holzmann; Horst Kessler 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 1 views

The tuning of protein ± protein interactions by small nonpeptidic molecules remains one of the great challenges in medicinal chemistry. Although already proposed in 1980 by Farmer, [1] only a few successful examples on the synthesis of peptidomimetics based on rigid scaffolds such as cyclohexane and

Design, Synthesis, and Biological Evalua

Design, Synthesis, and Biological Evaluation of Indole Derivatives as Novel Nociceptin/Orphanin FQ (N/OFQ) Receptor Antagonists.

✍ Yuichi Sugimoto; Atsushi Shimizu; Tetsuya Kato; Atsushi Satoh; Satoshi Ozaki; Hi 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 21 KB 👁 1 views