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Rational Design of Substrate-Based Multivalent Inhibitors of the Histone Acetyltransferase Tip60

✍ Scribed by Yang, Chao; Ngo, Liza; Zheng, Y. George


Book ID
121700710
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
269 KB
Volume
9
Category
Article
ISSN
1860-7179

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## Abstract The major histocompatibility complex (MHC)‐encoded transporter associated with antigen processing (TAP) translocates peptides from the cytosol into the lumen of the endoplasmic reticulum. This step precedes the binding of peptides to MHC class I molecules and is essential for cell surfa