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Rational design of peptide-based inhibitors of trypanothione reductase as potential antitrypanosomal drugs

✍ Scribed by J. Garforth; J. H. McKie; R. Jaouhari; T. J. Benson; A. H. Fairlamb; K. T. Douglas


Book ID
104953247
Publisher
Springer
Year
1994
Tongue
English
Weight
318 KB
Volume
6
Category
Article
ISSN
0939-4451

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## Abstract This study investigates a proposed design of a peptide sequence that is based on a bioactive conformation of statins that act as the competitive inhibitors of HMG–CoA for HMGR. To bridge these heterogeneous organic compounds, a conformational aspect relating to an analysis of the flexib