## Abstract Fabricating various nanostructures based on the selfβassembly of diverse biological molecules is now of great interest to the field of bionanotechnology. In this study, we report a de novo designed peptide (T1) with a preferential Ξ²βhairpin forming property that can spontaneously assemb
Rational Design of a Reversible pH-Responsive Switch for Peptide Self-Assembly
β Scribed by Zimenkov, Yuri; Dublin, Steven N.; Ni, Rong; Tu, Raymond S.; Breedveld, Victor; Apkarian, Robert P.; Conticello, Vincent P.
- Book ID
- 126780478
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 143 KB
- Volume
- 128
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
Peptide P 11 -4 (QQRFEWEFEQQ) was designed to self-assemble to form b-sheets and nematic gels in the pH range 5-7 at concentrations !12.6 mM in water. This self-assembly is reversibly controlled by adjusting the pH of the solvent. It can also self-assemble into gels in biological media. This togethe
## Abstract The selfβassembly of peptide YYKLVFFC based on a fragment of the amyloid beta (A__Ξ²__) peptide, A__Ξ²__16β20, KLVFF has been studied in aqueous solution. The peptide is designed with multiple functional residues to examine the interplay between aromatic interactions and charge on the sel