✦ LIBER ✦

Rates of sterol synthesis and hydroxymethylglutaryl coenzyme a reductase levels, and the effects of cholest-4-en-3-one on these parameters, in the livers of inbred strains of mice

✍ Scribed by Robert M. Packie; A. A. Kandutsch

Publisher: Springer
Year: 1970
Tongue: English
Weight: 658 KB
Volume: 4
Category: Article
ISSN: 0006-2928
DOI: 10.1007/bf00484031

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibitors of sterol synthesis. Chemical

Inhibitors of sterol synthesis. Chemical syntheses and spectral properties of 26-oxygenated derivatives of 3β-hydroxy-5α-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells

✍ Abdul U. Siddiqui; William K. Wilson; Karen E. Ruecker; Frederick D. Pinkerton; 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 974 KB

26-Oxygenated derivatives of As04)-15-ketosterols have been synthesized from (25R)-3#,26-diacetoxy-5a-cholest-8( )-en-15-one (IX) as part of a program to prepare potential metabolites and analogs of 3/~-hydroxy-5c~-cholest-8( )-en-15-one (I), a potent regulator of cholesterol metabolism. Partial hyd

Inhibitors of sterol synthesis. Chemical

Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of (25R)-5α-cholest-8(14)-ene-3β,15β,26-triol, a potential metabolite of 3β-hydroxy-5α-cholest-8(14)-en-15-one and its effects on 3-hydroxy-3-methylglutaryl-coenzyme A reductase in CHO-K1 cells

✍ Shankar Swaminathan; Frederick D. Pinkerton; William K. Wilson; George J. Schroe 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 570 KB

(25R)-5 alpha-Cholest-8(14)-ene-3 beta,15 beta,26-triol (III) was prepared by reduction of (25R)-3 beta,26-diacetoxy-5 alpha-cholest-8(14)-en-15-one with sodium borohydride followed by treatment of the crude product with lithium aluminium hydride. The trihydroxysterol III, a potential metabolite of