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Rate of chromosomal aberrations in prenatally detected hydrops fetalis and hygroma colli

✍ Scribed by G. Schwanitz; K. Zerres; U. Gembruch; R. Bald; M. Hansmann


Publisher
Springer
Year
1989
Tongue
English
Weight
102 KB
Volume
84
Category
Article
ISSN
0340-6717

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✦ Synopsis


Chromosome analyses were carried out in a series of 775 fetuses with morphological abnormalities diagnosed by ultrasound. Among these cases, 57 demonstrated non-immune hydrops fetalis with hygroma colli (group 1) and a further 116 non-immune hydrops fetalis without hygroma colli (group 2). Different chromosome abnormalities were found in 54.5% of cases of group 1 where chromosome analyses could be performed, and in 27.6% of cases of group 2. The most common aberrations were monosomy X and trisomy 21.