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Rate and orientation effect of TMEDA on directed lithiation reactions

✍ Scribed by D.W. Slocum; G. Book; C.A. Jennings


Publisher
Elsevier Science
Year
1970
Tongue
French
Weight
140 KB
Volume
11
Category
Article
ISSN
0040-4039

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✦ Synopsis


In view of recent reports of the ability of tetramethylethylenediamine (TMEDA) to increase the rates and yields of a number of metalation reactions,' examination of the effect


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Solvent and TMEDA Effects on the Configu
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## Abstract The employment of hexane/__N__,__N__,__N′__,__N′__‐tetramethylethylenediamine (TMEDA) dramatically hinders the racemization of those lithiated styrene oxides (trifluoromethyl‐, chloro‐, and phenylthio‐substituted) that have been proven to be configurationally unstable in THF on the time