Metabolism of polychlorinated dibenzo-p-
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Keke Hu; Nigel J. Bunce
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Article
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1999
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John Wiley and Sons
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English
โ 121 KB
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The in vitro metabolism of several chlorinated dibenzo-p-dioxin congeners (PCDDs) was studied using rat liver microsomes as a source of CYP 1 enzymes. The reactions were kinetically first order in both enzyme and substrate and showed a general trend toward decreasing reactivity with increasing chlor