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Rat metabolism of polychlorinated dibenzo-p-dioxins

โœ Scribed by M.Th.M. Tulp; O. Hutzinger


Book ID
119020558
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
322 KB
Volume
7
Category
Article
ISSN
0045-6535

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Metabolism of polychlorinated dibenzo-p-
โœ Keke Hu; Nigel J. Bunce ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 121 KB ๐Ÿ‘ 1 views

The in vitro metabolism of several chlorinated dibenzo-p-dioxin congeners (PCDDs) was studied using rat liver microsomes as a source of CYP 1 enzymes. The reactions were kinetically first order in both enzyme and substrate and showed a general trend toward decreasing reactivity with increasing chlor