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Rat liver ischemia–reperfusion-induced apoptosis and necrosis are decreased by FK506 pretreatment

✍ Scribed by Dominique Crenesse; Marina Laurens; Catherine Heurteaux; Raffaele Cursio; Marie Christine Saint-Paul; Annie Schmid-Alliana; Jean Gugenheim

Book ID
114015784
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
773 KB
Volume
473
Category
Article
ISSN
0014-2999

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## Abstract Necrosis was considered to be the solo mechanism for ischemia/reperfusion (I/R)‐induced cell death. Recent evidence from I/R models of the heart, liver, kidney, and brain indicates that apoptosis is a major contributor to I/R‐induced cell death. However, evidence of I/R‐induced apoptosi