Purification and substrate specificity o
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Feridoun Karimi-Busheri; Michael Weinfeld
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Article
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1997
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John Wiley and Sons
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English
⚖ 242 KB
Damage to DNA can result in strand breaks with 58-hydroxyl and 38-phosphate termini. Before DNA polymerases and ligases can rejoin the broken strands, such termini have to be restored to 58-phosphate and 38-hydroxyl groups. Polydeoxynucleotide kinase is an enzyme that may fulfil this function. We ha